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If the Indianapolis Colts fall Sunday night, it probably wouldn't be as devastating as the other recent losses they've been handed by the San Diego Chargers. Edwards white jerseyIt still would have to sting pretty badly.

The Chargers look to continue their latest second-half surge and send the Colts into a deeper funk by winning for the fifth time in the last six meetings. The struggles of Manning and the Colts (6-4) in those five games -- they've failed to score more than 24 points in any of them -- have plenty to do with the Chargers' defensive scheme, according to coach Norv Turner.

"I think that the 3-4 defense helps us defensively. I think that we've done a good job giving them a lot of different looks so we've been able to get pressure," he said. "And then we've been able to score points and keep the ball and that's a big part of playing good defense."
After opening 2-5, they've won three straight as Rivers has thrown for 10 touchdowns while the offense has averaged 32.7 points. San Diego has been below . 500 at least through five games in each of Turner's first three seasons but made the playoffs each time, and now it's within a game of Kansas City for the AFC West lead.

Indianapolis is tied atop the AFC South with Jacksonville but already has equaled its highest loss total since 2002. While their only win from the past three weeks saw the Colts struggle to beat woeful Cincinnati at home, Edwards blue jersey they lost at Philadelphia and New England in the other two as Manning threw interceptions with the game on the line.

"Peyton knows we're behind him 100 percent because we've seen him time and time again win games for us," cornerback Jerraud Powers said.

As Manning remains without two key targets with tight end Dallas Clark (wrist) out for the season and Austin Collie (concussion) missing his second game in three weeks, Rivers could welcome back two of his.
Vincent Jackson will make his long-awaited season debut after serving a three-game suspension on the team's roster exempt list following his contract holdout. The Pro Bowl receiver led San Diego last season with 1,167 receiving yards and nine touchdown receptions.